|Year : 2020 | Volume
| Issue : 3 | Page : 182-183
Primary ovarian leiomyoma
Shweta Raje, Sharda Arvind, Gayatri Rao, Latika Chawla
Department of Gynaec Endoscopy, Women' Hospital, Mumbai, Maharashtra, India
|Date of Submission||20-May-2019|
|Date of Decision||12-Nov-2019|
|Date of Acceptance||08-Jan-2020|
|Date of Web Publication||1-Aug-2020|
Dr. Sharda Arvind
Department of Gynaec Endoscopy, Women's Hospital, 674, 16th Cross Road, Behind Khar Gymkhana, Khar West, Mumbai - 400 052, Maharashtra
Source of Support: None, Conflict of Interest: None
Primary ovarian leiomyoma is an extremely rare form of extrauterine leiomyomas. The incidence of primary ovarian leiomyoma is 0.5%–1% of all benign ovarian smooth muscle tumors. We present a case of primary ovarian leiomyoma managed laparoscopically with ovarian preservation.
Keywords: Extrauterine leiomyoma, immunohistochemistry, laparoscopy, ovarian leiomyoma, rare leiomyoma
|How to cite this article:|
Raje S, Arvind S, Rao G, Chawla L. Primary ovarian leiomyoma. Gynecol Minim Invasive Ther 2020;9:182-3
We present a rare case of primary ovarian leiomyoma managed laparoscopically with ovarian preservation. A 31-year-old, P1 L1, female with regular menses had an incidental finding of right adnexal mass on ultrasound. Pelvic magnetic resonance imaging was suggestive of 5 cm × 4 cm × 4 cm, well-circumscribed, right ovarian solid mass with low-intensity signals on both T1 and T2 images [Figure 1]. Tumor markers were negative for ovarian malignancy. Intraoperative frozen section can be used to determine the nature of tumor. Intraoperatively, a solid right ovarian mass was seen. The ovarian surface was smooth. There were no adhesions to the surrounding structures. Uterus, left ovary, and both Fallopian tube More Detailss were unremarkable [Figure 2]. After making an incision on the ovarian capsule, sharp dissection was performed to carefully dissect the fibroid from the normal ovarian tissue. Laparoscopic excision of the right ovarian mass with contained tissue extraction and ovarian preservation was done [Figure 3]. Patient recovery was uneventful. Follow-up after 1 year did not show any recurrence. Histological examination showed strands of smooth muscle cells with ovoid nuclei arranged in whorled pattern. Immunohistochemistry showed positive staining for smooth muscle actin, confirming the diagnosis of ovarian leiomyoma [Figure 4].
|Figure 3: Laparoscopic excision of the right ovarian mass with ovarian preservation|
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|Figure 4: (a) Strands of smooth muscle cells with ovoid nuclei arranged in whorled pattern (H and E, ×40). (b) Smooth muscle actin immunostain: The tumor cells express smooth muscle actin|
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Primary ovarian leiomyoma is an extremely rare form of extrauterine leiomyomas. The incidence of primary ovarian leiomyoma is 0.5%–1% of all benign ovarian smooth muscle tumors., It may originate from smooth muscles of hilar vessels, undifferentiated germ cells in ovarian stroma, ovarian ligament, stroma of endometriosis, and remnant of Wolffian body., Most of these tumors are unilateral, small in size, and occur in premenopausal women. The differential diagnoses for primary ovarian leiomyoma include broad-ligament fibroid, subserous adenexal pedunculated fibroid, solid ovarian stromal tumor, secondary involvement of ovarian hilar vessels in case of intravenous leiomyomatosis, and leiomyomatosis peritonealis disseminate. It may be difficult to distinguish between ovarian fibroma and leiomyoma intraoperatively. Histopathology and immunochemical analysis confirm the diagnosis. Although ovarian leiomyomas are benign, the usual approach has been oophorectomy considering the solid nature of tumor. Laparoscopic management with ovarian preservation can be considered with appropriate preoperative evaluation to rule out ovarian malignancy.
The study was approved by the institutional ethics committee of Women's Hospital, Mumbai (IRB approval number 1066/2018 obtained on March 5th, 2019).
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form the patient has given her consent for her images and other clinical information to be reported in the journal. The patient understands that her name and initials will not be published and due efforts will be made to conceal her identity, but anonymity cannot be guaranteed.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Kim M. Laparoscopic management of a twisted ovarian leiomyoma in a woman with 10 weeks' gestation: Case report and literature review. Medicine (Baltimore) 2016;95:e5319.
Taskin MI, Ozturk E, Yildirim F, Ozdemir N, Inceboz U. Primary ovarian leiomyoma: A case report. Int J Surg Case Rep 2014;5:665-8.
[Figure 1], [Figure 2], [Figure 3], [Figure 4]